Rochester (NY): University of Rochester Medical Center c2022. University of Rochester Medical Center.Blood Test: Immunoglobulins (IgA, IgG, IgM). Jacksonville (FL): The Nemours Foundation c1995–2022. Test ID: IMMG: Immunoglobulins (IgG, IgA, and IgM), Serum: Clinical and Interpretative. Mayo Foundation for Medical Education and Research c1995–2022. Mayo Clinic: Mayo Medical Laboratories.Treasure Island (FL): StatPearls Publishing 2022 Jan. Justiz Vaillant AA, Jamal Z, Ramphul K.Quantitative Immunoglobulins: IgA, IgG, and IgM 442–3 p. Philadelphia: Wolters Kluwer Health, Lippincott Williams & Wilkins c2014.

Brunner & Suddarth's Handbook of Laboratory and Diagnostic Tests. Learn more about laboratory tests, reference ranges, and understanding results. If you have questions about your results, talk with your provider. Certain medicines can affect your results. If your immunoglobulin levels aren't normal, it doesn't always mean you have a condition that needs treatment. These cancers often cause a very high level of one type of immunoglobulin and low levels for the other types: Some possible causes of high levels of one or more immunoglobulins are: A genetic disease that you were born with, such as common variable immunodeficiency disorder (CVID).Conditions that affect your ability to make immunoglobulins, including:.Conditions that may reduce the amount of protein in your body, including:.Some possible causes of low levels of one or more immunoglobulins are: So if your results aren't normal, you'll probably need more testing to find out what's affecting your immune system. An immunoglobulins blood test alone cannot diagnose any conditions. Your results can mean different things, depending on which immunoglobulins are high or low, your symptoms, and any conditions you may have. Your provider will compare your levels of IgM, IgG, and IgA. So, even though your levels are high, you may have frequent infections and other symptoms of low immunoglobulin levels. But those immunoglobulins don't work normally. These cancers may cause a very high level of certain immunoglobulins.

You may also need this test if your provider thinks you may have high levels of immunoglobulins from an autoimmune disease or a cancer that affects your blood, bone marrow, and/or immune system. You may need an immunoglobulins test if immunodeficiency runs in your family, or your health care provider thinks you may have a problem making normal levels of immunoglobulins.

A yeast infection in the mouth, eyes, or digestive tract (thrush).

Cytomegalovirus (a virus related to chickenpox).

Serious infections from germs that don't usually cause problems in healthy people, such as:.

Respiratory infections, such as pneumonia and bronchitis.

Symptoms of low levels of immunoglobulins usually include having many, repeated infections and other problems, such as: If you have too few immunoglobulins, you have an immunodeficiency. You may need this test if you have symptoms that could mean your immunoglobulin levels are too low. Why do I need an immunoglobulins blood test? Other names: quantitative immunoglobulins, total immunoglobulins, IgG, IgM, IgA testing You have IgA antibodies in your blood, saliva, and gastric 'juices.'Īn immunoglobulins blood test measures the amounts of IgM, IgG, and IgA in your blood to help diagnose different types of health conditions that may affect your immune system.

IgA antibodies protect your respiratory tract (the organs you use to breathe) and your digestive system (the organs you use to eat and digest food) from infections.

That way, if you're exposed to the same germs again, your immune system can quickly make more antibodies. Your body keeps a 'blueprint' of all the IgG antibodies you have made. You also have some IgG antibodies in all your body fluids. Most of the immunoglobulins in your blood are IgG.

IgG antibodies are very important for fighting infections from bacteria and viruses.

IgM antibodies are in your blood and lymph fluid (a watery fluid that carries the cells that fight infections and diseases to all parts of your body). They provide short-term protection while your body makes other antibodies.

IgM antibodies are the first immunoglobulins your body makes after you're exposed to germs.

When you're exposed to germs, your body makes unique antibodies that are specifically designed to destroy only those germs.Īn immunoglobulins test usually measures three main types of immunoglobulin (Ig) antibodies that do different jobs to protect your health: Antibodies are proteins that your immune system makes to fight germs, such as viruses and bacteria. Immunoglobulins are also called antibodies. This test measures the amount of immunoglobulins in your blood.

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